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Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells.

Authors
  • Baradari, Viola
  • Höpfner, Michael
  • Huether, Alexander
  • Schuppan, Detlef
  • Scherübl, Hans
Type
Published Article
Journal
World Journal of Gastroenterology
Publisher
Baishideng Publishing Group Co
Publication Date
Sep 07, 2007
Volume
13
Issue
33
Pages
4458–4466
Identifiers
PMID: 17724801
Source
Medline
License
Unknown

Abstract

The growth of human cholangiocarcinoma cells can be potently inhibited by MS-275 alone or in combination with conventional cytostatic drugs or new, targeted anticancer agents.

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