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Histomorphometric analysis of epithelial changes in chemically induced oral mucosal carcinogenesis in rats.

Authors
Type
Published Article
Journal
Journal of oral pathology
0300-9777
Publication Date
Volume
17
Issue
9-10
Pages
528–533
Identifiers
PMID: 3150440
Source
Medline
License
Unknown

Abstract

Quantitative analysis of rat palatal mucosa after the carcinogen 4- nitroquinoline-1-oxide had been applied to the epithelium for varying periods of time showed that there was a significant increase in epithelial thickness, due largely to an increase in thickness of the basal compartment. This alteration was measurable before epithelial dysplasia could be recognised.

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