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Histological characteristics of sternoclavicular beta 2-microglobulin amyloidosis and clues for its histogenesis.

Authors
  • Garbar, C
  • Jadoul, M
  • Noël, H
  • van Ypersele de Strihou, C
Type
Published Article
Journal
Kidney international
Publication Date
May 01, 1999
Volume
55
Issue
5
Pages
1983–1990
Identifiers
PMID: 10231463
Source
Medline
License
Unknown

Abstract

The earliest stage of A beta 2m deposition occurs in the cartilage. A beta 2m subsequently extends to capsule and synovium. These two first stages do not require macrophage infiltration. Macrophages are eventually recruited around larger synovial or capsular deposits in the final stage. Marginal bone erosions develop in this late stage.

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