Affordable Access

Histologic grading and the practicing urologist.

Authors
  • Albertsen, P
Type
Published Article
Journal
The Prostate
Publication Date
Jan 01, 1982
Volume
3
Issue
4
Pages
333–338
Identifiers
PMID: 7122330
Source
Medline
License
Unknown

Abstract

Over the past 60 years, pathologists have identified three histologic features, tumor volume, glandular differentiation, and nuclear anaplasia, as important prognosticators of the malignant potential of prostatic adenocarcinoma. Several histologic grading systems have emerged to assess these morphological and cytological features, but problems with objectivity and reproducibility have been encountered. The failure of grading systems to predict accurately the malignant potential of individual tumors and the paucity of therapeutic options available have prevented many urologists from adopting these systems. Recent progress among stage A lesions has highlighted the clinical relevance of histologic grading systems, but advances are needed in prognostic techniques and therapeutic modalities before the practicing urologist can apply histologic information clinically among the majority of his patients.

Report this publication

Statistics

Seen <100 times