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Histologic grading of noninvasive papillary urothelial neoplasms.

Authors
  • MacLennan, Gregory T
  • Kirkali, Ziya
  • Cheng, Liang
Type
Published Article
Journal
European urology
Publication Date
Apr 01, 2007
Volume
51
Issue
4
Identifiers
PMID: 17095142
Source
Medline
License
Unknown

Abstract

The 2004 WHO classification is a positive initiative in attempting to standardize urothelial tumor grading by expanding and clearly defining the morphologic characteristics of noninvasive papillary urothelial neoplasms. The new terminology used in this system is of questionable validity and utility. Full-genome searches for prognostic and predictive molecular gene expression signatures, GeneChip technology and proteomics techniques, and several new biomarkers and molecular tests may be useful in future grading schemes after their clinical utility is better established.

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