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[Histoenzymologic features of adrenal medulla ganglionic cells 60 days after exposure to detergents].

Authors
  • Devecerski, V
  • Marjanov, M
  • Milićević, S
Type
Published Article
Journal
Medicinski pregled
Publication Date
Jan 01, 1993
Volume
46
Issue
5-6
Pages
181–184
Identifiers
PMID: 7869971
Source
Medline
License
Unknown

Abstract

We investigated histochemical reactions in adrenal medulla sympathic ganglionic cells in the animals who after a 30-day stay in a detergent manufactory department survived 60 days in laboratory conditions. The obtained data show a strong isocytrate dehydrogenase activity in the experimental animals; the reaction to the lactate dehydrogenase activity reflects a decrease of the ganglionic cell volume and a slight decrease of the reaction intensity. The activity of isoenzyme F is mildly increased; similarly was found for isoenzyme S. There was a significant decrease of the succinate dehydrogenase activity--all this was detected in the animals exposed to detergents. Sympathic ganglionic cells within the adrenal medulla are rather sensitive to the influence of detergents. The recovery after the exposure to their toxic effects takes more than 2 months.

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