Affordable Access

deepdyve-link
Publisher Website

Highly sensitive detection of telomerase based on a DNAzyme strategy.

Authors
  • Tian, Tian1
  • Peng, Shuang
  • Xiao, Heng
  • Zhang, Xiaoe
  • Guo, Shan
  • Wang, Shaoru
  • Zhou, Xiang
  • Liu, Songmei
  • Zhou, Xin
  • 1 College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, Wuhan University, Wuhan, Hubei 430072, PR China. , (China)
Type
Published Article
Journal
Chemical Communications
Publisher
The Royal Society of Chemistry
Publication Date
Apr 04, 2013
Volume
49
Issue
26
Pages
2652–2654
Identifiers
DOI: 10.1039/c3cc38818b
PMID: 23435369
Source
Medline
License
Unknown

Abstract

The present study demonstrated a highly sensitive strategy for measuring telomerase activity in cell extracts. Furthermore, we applied the new strategy for in situ detection of telomerase at the cellular level in cancer cells, together with a normal cell as the negative control.

Report this publication

Statistics

Seen <100 times