Day by day, humans and animals are infected with life-threatening and deadly diseases due to mosquito bites. Current methods used to fight these diseases are not fully viable and unsafe for humans and animals. Controlling the germ-carrying mosquitoes requires the immediate transfer of a conceptual paradigm. This experiment suggested a safe mosquito control mechanism with fluorescence iron-oxide core carbon-coated ([email protected]) nontoxic nanoparticles used as an active agent. As the concept of experiment, we chose mosquitoes of Anopheles, Aedes, and Culex genera because they are found worldwide and infect pathogens. The progression of the life cycle of mosquitoes was observed and imaging under the treated known concentration of [email protected] nanoparticles. Resulted that a minimum 3 mg/L and above concentration of [email protected] nanoparticles in breeding water these group of larvae can't attend their adulthood and ultimately died under prolong stay in the larval stage. In this case, though the species can be studied for a sustained time the originality of the wild species is lost.