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A high-throughput microfluidic dental plaque biofilm system to visualize and quantify the effect of antimicrobials.

Authors
  • Nance, William C
  • Dowd, Scot E
  • Samarian, Derek
  • Chludzinski, Jeffrey
  • Delli, Joseph
  • Battista, John
  • Rickard, Alexander H
Type
Published Article
Journal
Journal of Antimicrobial Chemotherapy
Publisher
Oxford University Press
Publication Date
Nov 01, 2013
Volume
68
Issue
11
Pages
2550–2560
Identifiers
DOI: 10.1093/jac/dkt211
PMID: 23800904
Source
Medline
Keywords
License
Unknown

Abstract

This work demonstrates the utility of a high-throughput microfluidic-CLSM system to grow multi-species oral biofilms, which are compositionally similar to naturally occurring biofilms, to assess the effectiveness of antimicrobials.

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