[High pressure liquid-liquid chromatography: correlation between retention times and biological activity of 1,3,5-triazine derivatives].
- Published Article
Il Farmaco; edizione scientifica
- Publication Date
Jan 01, 1976
An investigation has been made of the possibility of using the retention times t obtained by reversed phase high pressure liquid-liquid chromatography in the study of quantitative structure-activity relatiionships. Taking as an example a group of herbicides which inhibit the Hill reaction, it was found that log t is additive and can be used as the hydrophobic parameter in regression analyses. The characteristics, advantages and possible developments of the method are discussed and the analytical interest is highlighted.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/939320