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High level of glutathione-S-transferase pi expression in mantle cell lymphomas.

Authors
  • Bennaceur-Griscelli, Annelise
  • Bosq, Jacques
  • Koscielny, Serge
  • Lefrère, François
  • Turhan, Ali
  • Brousse, Nicole
  • Hermine, Olivier
  • Ribrag, Vincent
Type
Published Article
Journal
Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Date
May 01, 2004
Volume
10
Issue
9
Pages
3029–3034
Identifiers
PMID: 15131039
Source
Medline
License
Unknown

Abstract

Overexpression of CCND1 in MCL is associated with a transcriptional up-regulation of the GST-pi gene. Our results suggest that the glutathione system could play a role in drug resistance in MCL.

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