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High-grade transformation of adenoid cystic carcinomas: a study of the expression of GLUT1 glucose transporter and of mitochondrial antigen.

Authors
  • Bonfitto, V L
  • Demasi, A P
  • Costa, A F
  • Bonfitto, J F
  • Araujo, V C
  • Altemani, A
Type
Published Article
Journal
Journal of Clinical Pathology
Publisher
BMJ
Publication Date
Jul 01, 2010
Volume
63
Issue
7
Pages
615–619
Identifiers
DOI: 10.1136/jcp.2010.075390
PMID: 20530155
Source
Medline
License
Unknown

Abstract

Transformation of classical ACC into ACC-HGT encompasses adenocarcinomas with variable degrees of differentiation and seems to lead to metabolic changes without reflection in tumour vasculature. Despite the tumours' higher GLUT1 expression, this protein has no utility as a prognostic marker.

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