High-density allelotyping of chromosome 8p in hepatocellular carcinoma and clinicopathologic correlation.
- Published Article
- Publication Date
Jun 15, 2002
Allelic losses on 8p are frequent in HCC patients. Association of allelic losses at specific loci on 8p with a more aggressive tumor behavior suggests that loss/inactivation of putative tumor suppressor gene(s) located at these regions may confer a tumor growth advantage and contribute to the progression of HCC.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/12115350