Affordable Access

High-density allelotyping of chromosome 8p in hepatocellular carcinoma and clinicopathologic correlation.

Authors
  • Chan, Kok-Lung
  • Lee, Joyce Man-Fong
  • Guan, Xin-Yuan
  • Fan, Sheung-Tat
  • Ng, Irene Oi-Lin
Type
Published Article
Journal
Cancer
Publication Date
Jun 15, 2002
Volume
94
Issue
12
Pages
3179–3185
Identifiers
PMID: 12115350
Source
Medline
License
Unknown

Abstract

Allelic losses on 8p are frequent in HCC patients. Association of allelic losses at specific loci on 8p with a more aggressive tumor behavior suggests that loss/inactivation of putative tumor suppressor gene(s) located at these regions may confer a tumor growth advantage and contribute to the progression of HCC.

Report this publication

Statistics

Seen <100 times