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High-density allelotyping of chromosome 8p in hepatocellular carcinoma and clinicopathologic correlation.

Authors
Type
Published Article
Journal
Cancer
Publication Date
Volume
94
Issue
12
Pages
3179–3185
Identifiers
PMID: 12115350
Source
Medline
License
Unknown

Abstract

Allelic losses on 8p are frequent in HCC patients. Association of allelic losses at specific loci on 8p with a more aggressive tumor behavior suggests that loss/inactivation of putative tumor suppressor gene(s) located at these regions may confer a tumor growth advantage and contribute to the progression of HCC.

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