Affordable Access

Hidroacanthoma simplex: an ultrastructural and immunohistochemical study.

Authors
  • Perniciaro, C
  • Muller, S A
  • Zelickson, B D
  • Snow, J L
Type
Published Article
Journal
Journal of cutaneous pathology
Publication Date
Jun 01, 1994
Volume
21
Issue
3
Pages
274–279
Identifiers
PMID: 7962831
Source
Medline
License
Unknown

Abstract

A representative case of hidroacanthoma simplex was studied with routine light microscopy, immunohistochemistry, and electron microscopy. Staining with the periodic acid-Schiff reagent and immunostaining with anti-keratin antibodies were useful in demarcating the tumor cells from adjacent normal epithelium. However, antibodies to carcinoembryonic antigen and epithelial membrane antigen did not help us to segregate or identify the neoplastic cells. Electron microscopy revealed tumor cells markedly different in appearance from luminal cells of the acrosyringium. Hidroacanthoma simplex does not appear to be derived from luminal cells of the acrosyringium. We propose criteria for the histologic diagnosis of this benign neoplasm.

Report this publication

Statistics

Seen <100 times