Herpes simplex virus keratitis: an update of the pathogenesis and current treatment with oral and topical antiviral agents.
Royal Eye Infirmary, Dorset County Hospital NHS Foundation Trust, Dorchester, UK.
Southampton University Hospitals NHS Foundation Trust, Southampton, UK.
Moorfields Eye Hospital NHS Foundation Trust, London, UK.
University of Athens, Athens, Greece.
- Published Article
Clinical & experimental ophthalmology
- Publication Date
Ophthalmic herpes simplex viral keratitis is responsible for a range of ocular manifestations from superficial epithelial disease to stromal keratitis and endotheliitis. The Herpetic Eye Disease Study has guided the management of herpetic eye disease for almost twenty years, but newer medications such as valacyclovir are now available and are considered to have better bioavailability than acyclovir. In this review, we examine the existing evidence on the pathogenesis of different ophthalmic herpes simplex viral keratitis disease modalities and the role of oral and topically administered antiviral drugs in the treatment of herpes simplex viral keratitis.
Report this publication
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 07/07/2017 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/27273328