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Hereditary spherocytosis in a patient undergoing coronary artery bypass grafting with cardiopulmonary bypass--a case report.

Authors
Type
Published Article
Journal
Perfusion
1477-111X
Publisher
SAGE Publications
Publication Date
Volume
30
Issue
1
Pages
77–81
Identifiers
DOI: 10.1177/0267659114529323
PMID: 24714521
Source
Medline
Keywords
  • Cardiac Surgery
  • Cardiopulmonary Bypass
  • Haemolysis
  • Hereditary Spherocytosis

Abstract

Hereditary spherocytosis is a genetically determined abnormality of red blood cells. It is the most common cause of inherited haemolysis in Europe and North America within the Caucasian population. We document a patient who underwent an aortocoronary bypass procedure on cardiopulmonary bypass. In view of the uncertain tolerance of the abnormal red cells in hereditary spherocytosis to cardiopulmonary bypass, we reviewed the patient's chart and analyzed recorded values of these parameters: free plasma haemoglobin, renal parameters, cystatin C, bilirubin, liver tests, urine samples. From the results, we can see that slight haemolysis-elevated bilirubin in the blood sample and elevated bilirubin and urobilinogen in the urine sample occurred on the first postoperative day. The levels of these parameters slowly decreased during the next postoperative days. There was no real clinical effect of this haemolysis on renal functions.

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