Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Herbal antioxidant in clinical practice: a review.

Authors
  • Alok, Shashi1
  • Jain, Sanjay Kumar
  • Verma, Amita
  • Kumar, Mayank
  • Mahor, Alok
  • Sabharwal, Monika
  • 1 Institute Of Pharmacy, Bundelkhand University, Jhansi (U.P.), India; Department of Pharmaceutical Sciences, Faculty of Health Sciences, Sam Higginbottom Institute of Agriculture, Technology and Sciences-Deemed University, Allahabad, U.P. India. Electronic address: [email protected] , (India)
Type
Published Article
Journal
Asian Pacific Journal of Tropical Biomedicine
Publisher
Medknow Publications
Publication Date
Jan 01, 2014
Volume
4
Issue
1
Pages
78–84
Identifiers
DOI: 10.1016/S2221-1691(14)60213-6
PMID: 24144136
Source
Medline
Keywords
License
Unknown

Abstract

Antioxidant-the word itself is magic. Using the antioxidant concept as a spearhead in proposed mechanisms for staving off so-called "free-radical" reactions, the rush is on to mine claims for the latest and most effective combination of free-radical scavenging compounds. We must acknowledge that such "radicals" have definitively been shown to damage all biochemical components such as DNA/RNA, carbohydrates, unsaturated lipids, proteins, and micronutrients such as carotenoids (alpha and beta carotene, lycopene), vitamins A, B6, B12, and folate. Defense strategies against such aggressive radical species include enzymes, antioxidants that occur naturally in the body (glutathione, uric acid, ubiquinol-10, and others) and radical scavenging nutrients, such as vitamins A, C, and E, and carotenoids. This paper will present a brief discussion of some well- and little-known herbs that may add to the optimization of antioxidant status and therefore offer added preventive values for overall health. It is important to state at the outset that antioxidants vary widely in their free-radical quenching effects and each may be individually attracted to specific cell sites. Further evidence of the specialized nature of the carotenoids is demonstrated by the appearance of two carotenoids in the macula region of the retina where beta-carotene is totally absent.

Report this publication

Statistics

Seen <100 times