Immunohistochemical determination of HNF4α expression is an effective tool for distinguishing different AC subtypes. Similarly, HNF4α protein expression is an independent predictor of favorable prognosis in carcinoma of the papilla of Vater and may serve for risk stratification after curative resection.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/21494118