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Hepatocyte nuclear factor (HNF) 4α expression distinguishes ampullary cancer subtypes and prognosis after resection.

Authors
Type
Published Article
Journal
Annals of Surgery
0003-4932
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Volume
254
Issue
2
Pages
302–310
Identifiers
DOI: 10.1097/SLA.0b013e31821994a8
PMID: 21494118
Source
Medline

Abstract

Immunohistochemical determination of HNF4α expression is an effective tool for distinguishing different AC subtypes. Similarly, HNF4α protein expression is an independent predictor of favorable prognosis in carcinoma of the papilla of Vater and may serve for risk stratification after curative resection.

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