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Hepatocellular carcinoma risk factors and disease burden in a European cohort: a nested case-control study.

Authors
  • And 26 more
Type
Published Article
Journal
JNCI Journal of the National Cancer Institute
1460-2105
Publisher
Oxford University Press
Publication Date
Volume
103
Issue
22
Pages
1686–1695
Identifiers
DOI: 10.1093/jnci/djr395
PMID: 22021666
Source
Medline
License
Unknown

Abstract

Smoking contributed to more hepatocellular carcinomas in this Europe-wide cohort than chronic HBV and HCV infections. Heavy alcohol consumption and obesity also contributed to sizeable fractions of this disease burden. These contributions may be underestimates because EPIC volunteers are likely to be more health conscious than the general population.

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