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Hepatitis C antibodies in patients with alcoholic liver disease commonly have an identifiable risk factor.

Authors
Type
Published Article
Journal
Journal of Clinical Gastroenterology
0192-0790
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Volume
15
Issue
3
Pages
233–235
Identifiers
PMID: 1336022
Source
Medline
License
Unknown

Abstract

Hepatitis C virus (HCV) antibodies detected by radioimmunoassay (RIA) and immunoblot assay were determined in 139 patients with alcoholic liver disease (ALD). Risk factors for exposure to HCV were recorded. Anti-HCV was detected by RIA in 38 (27%), but only 18 (13%) were confirmed with an immunoblot assay. One hundred seven (77%) had risk factors. Of these 107, anti-HCV was detected in 36 by RIA and in 17 by immunoblot assay. Only 2 of 32 patients without risk factors had anti-HCV detected by RIA (1 was reactive with immunoblot, p < 0.05 vs. patients with risk factors). Parenteral drug use and multiple heterosexual contacts were significantly associated with anti-HCV. Age, sex, duration of alcoholism, race, and birthplace did not correlate with detectable HCV antibodies.

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