Affordable Access

Hepatic and renal effects of low concentrations of methoxyflurane in exposed delivery ward personnel.

Authors
  • Dahlgren, B E
Type
Published Article
Journal
Journal of occupational medicine. : official publication of the Industrial Medical Association
Publication Date
Dec 01, 1980
Volume
22
Issue
12
Pages
817–819
Identifiers
PMID: 7218059
Source
Medline
License
Unknown

Abstract

During five alternating three-week periods either methoxyflurane-nitrous oxide or nitrous oxide alone was used for obstetrical analgesia. Delivery ward personnel were followed by venous blood samples once a week. Analyses of blood urea nitrogen, serum uric acid, SGOT and SGPT showed significantly elevated levels three days after exposure to methoxyflurane. This study demonstrates the importance of the scavenging of anesthetic gases to reduce the exposure of personnel to inhalational agents used in delivery suites. Since definite alterations in the indices of both hepatic and renal functions were recognized in obstetrical personnel following exposure, a re-evaluation of the use of methoxyflurane for obstetrical analgesia is suggested.

Report this publication

Statistics

Seen <100 times