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Hepatic encephalopathy presenting as delirium and mania. The possible role of bilirubin.

Authors
Type
Published Article
Journal
General Hospital Psychiatry
0163-8343
Publisher
Elsevier
Publication Date
Volume
16
Issue
2
Pages
138–140
Identifiers
PMID: 8039693
Source
Medline
License
Unknown

Abstract

The case of a woman who suffered from hepatic encephalopathy is described. The psychiatric symptoms presented first as a delirium, changing into a manic syndrome. As the neurotoxic direct fraction of bilirubin was greater than 100 times normal, increasing and decreasing in a parallel fashion with the psychiatric symptoms, direct bilirubin is assumed to play a role in the pathogenesis of this case. This is discussed in the context of bilirubin encephalopathy, very seldom diagnosed in adults.

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