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[Hepatic arterial chemotherapy for liver cancer over a period of 8 years].

Authors
  • Masutani, S
  • Tatsuta, M
  • Kawasaki, T
  • Morimoto, O
  • Tsuji, Y
  • Shiozaki, K
  • Baba, S
  • Miya, A
  • Ishida, H
  • Satomi, T
Type
Published Article
Journal
Gan to kagaku ryoho. Cancer & chemotherapy
Publication Date
Sep 01, 1997
Volume
24
Issue
12
Pages
1656–1659
Identifiers
PMID: 9382500
Source
Medline
License
Unknown

Abstract

Hepatic arterial chemotherapy was performed for 27 patients with primary (3), metastatic liver cancer (21), and 3 other cases, over a period of 8 years. Chemotherapy was performed by intermittent hepatic arterial infusion of 5-FU or FAM (in case of metastatic tumor from colorectal cancer), FAM (from gastric cancer), and CDDP or Farmorubicin (HCC). Hepatic resection was performed in 10 cases of metastatic tumor from colorectal cancer, and 8 cases of 10 were curative operation. The 5-year survival rates of curative liver resection group, and non-curative liver resection or non-resection group were 57.1% and 12.5%, respectively. As is the case with metastatic cancer from gastric cancer, pancreatic cancer, and hepatocellular carcinoma (HCC), the prognosis was poor except for one CR case of HCC. We concluded that hepatic arterial chemotherapy may be recommended for a curative resected case of liver metastasis from colorectal cancer.

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