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Hepatectomy is a Reasonable Option for Older Patients with Hepatocellular Carcinoma

Authors
  • Cho, Bong Ick
  • Kim, Jong Man
  • David Kwon, Choon Hyuck
  • Joh, Jae-Won
  • Park, Jae Berm
  • Lee, Joon Hyeok
  • Kim, Sung Joo
  • Paik, Seung Woon
  • Park, Cheol Keun
Type
Published Article
Journal
The American Journal of Surgery
Publisher
Elsevier
Publication Date
Jan 01, 2013
Accepted Date
Jun 14, 2013
Identifiers
DOI: 10.1016/j.amjsurg.2013.06.010
Source
Elsevier
Keywords
License
Unknown

Abstract

BackgroundHepatic resection is the main treatment for patients with hepatocellular carcinoma(HCC). However, surgery is generally stressful for older patients. MethodsClinicopathological data and outcomes after hepatic resection were retrospectively investigated for older HCC patients. The younger group(n=219) included patients between 60 and 69 years old, and the older group(n=60) included patients older than 70 years. ResultsHepatitis B virus was more common in the younger group than in the older group(64.5% vs. 28.8%, P<0.001). The occurrence of pneumonia was higher in older group than in the younger group(10.0% vs. 2.3%, P=0.015), but postoperative complications and mortality were not significantly different between the two groups. There was no statistically significant difference in disease-free survival rates between the two groups. ConclusionsAlthough the incidence of postoperative pneumonia was higher in the older group than in the younger group, hepatic resection was justified for HCC in selected patients older than 70 years.

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