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Hematopoietic stem cell transplantation in hemophagocytic lymphohistiocytosis: a single-center report of 48 patients.

Authors
  • Ouachée-Chardin, Marie
  • Elie, Caroline
  • de Saint Basile, Geneviève
  • Le Deist, Françoise
  • Mahlaoui, Nizar
  • Picard, Capucine
  • Neven, Bénédicte
  • Casanova, Jean-Laurent
  • Tardieu, Marc
  • Cavazzana-Calvo, Marina
  • Blanche, Stéphane
  • Fischer, Alain
Type
Published Article
Journal
PEDIATRICS
Publisher
American Academy of Pediatrics
Publication Date
Apr 01, 2006
Volume
117
Issue
4
Identifiers
PMID: 16549504
Source
Medline
License
Unknown

Abstract

This survey demonstrates the long-term efficacy of HSCT as a cure of FHLH. HSCT preserves quality of life. It shows that HSCT should be performed as early as a complete remission has been achieved. Additional studies are required to improve the procedure and reduce its toxic effects.

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