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Heat shock. A new approach for myocardial preservation in cardiac surgery.

Authors
  • Liu, X
  • Engelman, R M
  • Moraru, I I
  • Rousou, J A
  • Flack, J E 3rd
  • Deaton, D W
  • Maulik, N
  • Das, D K
Type
Published Article
Journal
Circulation
Publication Date
Nov 01, 1992
Volume
86
Issue
5 Suppl
Identifiers
PMID: 1424025
Source
Medline
License
Unknown

Abstract

The results show that preconditioning the heart with HS improves postischemic ventricular performance and attenuates cellular injury. HS induces a change in cellular metabolism, prompting the expression of HSP and improving antioxidant activity, leading to improved function and reduced tissue injury during ischemia and reperfusion.

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