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Hearing loss and nephrotoxicity in long-term aminoglycoside treatment in patients with tuberculosis.

Authors
  • de Jager, P
  • van Altena, R
Type
Published Article
Journal
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
Publication Date
Jul 01, 2002
Volume
6
Issue
7
Pages
622–627
Identifiers
PMID: 12102302
Source
Medline
License
Unknown

Abstract

Patients developing nephrotoxicity had a significantly longer duration of treatment with aminoglycosides, and received a larger total dose. We did not find any factor significantly associated with the development of hearing loss. In the long-term treatment of tuberculosis with aminoglycosides, ototoxicity seems to be a greater problem than nephrotoxicity.

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