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HCC in young adults.

Authors
  • Carr, Brian I
  • Pancoska, Petr
  • Branch, Robert A
Type
Published Article
Journal
Hepato-gastroenterology
Publication Date
Jan 01, 2010
Volume
57
Issue
99-100
Pages
436–440
Identifiers
PMID: 20698204
Source
Medline
License
Unknown

Abstract

A large cohort of unresectable and untransplantable biopsy-proven HCC patients was rank-ordered for survival. Non-random clustering by age was noted, with 3 sub-cohorts of younger patients with survival in the range of 90-360 days. One sub-cohort had a predominance of females. Tumor numbers were well monitored by serum AFP, but tumor mass was better monitored by serum GGTP. In contrast to the older patients, the probability of hepatitis appeared to have a major impact on their survival and these patients tended to have larger numbers of smaller tumors, consistent with the idea of a hepatitis-mediated carcinogenic field defect.

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