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The haptoglobin promoter polymorphism rs5471 is the most definitive genetic determinant of serum haptoglobin level in a Ghanaian population.

Authors
  • Soejima, Mikiko1
  • Teye, Kwesi1
  • Koda, Yoshiro2
  • 1 Department of Forensic Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan. , (Japan)
  • 2 Department of Forensic Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan. Electronic address: [email protected] , (Japan)
Type
Published Article
Journal
Clinica chimica acta; international journal of clinical chemistry
Publication Date
Aug 01, 2018
Volume
483
Pages
303–307
Identifiers
DOI: 10.1016/j.cca.2018.05.029
PMID: 29772214
Source
Medline
Keywords
License
Unknown

Abstract

We suggest that rs5471 is a strong genetic determinant of HP levels in Ghanaians, and this seems to be characteristic of Africans. Further investigation using large scale samples will help in understanding the genetic background of individual variability of the serum HP level.

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