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Halothane-dependent lipid peroxidation in human liver microsomes is catalyzed by cytochrome P4502A6 (CYP2A6).

Authors
  • Minoda, Y1
  • Kharasch, E D
  • 1 University of Washington, Department of Anesthesiology and Medicinal Chemistry, Seattle 98195, USA.
Type
Published Article
Journal
Anesthesiology
Publication Date
August 2001
Volume
95
Issue
2
Pages
509–514
Identifiers
PMID: 11506127
Source
Medline
License
Unknown

Abstract

Halothane causes lipid peroxidation in human liver microsomes, which is catalyzed by CYP2A6, and inhibition of halothane reduction prevents halothane-dependent lipid peroxidation in vitro.

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