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Haemophagocytic lymphohistiocytosis in a patient with severe burns.

Authors
Type
Published Article
Journal
Anaesthesia
1365-2044
Publisher
Wiley Blackwell (Blackwell Publishing)
Publication Date
Volume
68
Issue
4
Pages
413–416
Identifiers
DOI: 10.1111/anae.12062
PMID: 23121294
Source
Medline
License
Unknown

Abstract

Recently, increasing attention has been drawn to haemophagocytic lymphohistiocytosis as a potentially under-diagnosed condition in critically ill patients with severe sepsis. It is thought to be caused by a highly stimulated, but ineffective, immune system. We report the case of a patient suffering from major burns who, despite extensive investigations showing the absence of concurrent sepsis or infection, developed haemophagocytic lymphohistiocytosis refractory to treatment. We believe that this is the first report suggestive of haemophagocytic lymphohistiocytosis triggered by a burns injury.

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