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Haemodynamic effects of intravenous quinaprilat in comparison to sodium nitroprusside in patients with chronic heart failure.

Authors
  • Kieback, Arne G
  • Grohmann, Andrea
  • Baumann, Gert
  • Felix, Stephan B
Type
Published Article
Journal
International Journal of Cardiology
Publisher
Elsevier
Publication Date
Sep 14, 2007
Volume
121
Issue
1
Pages
102–104
Identifiers
PMID: 17098309
Source
Medline
License
Unknown

Abstract

We compared the haemodynamic effects of intravenous boluses of the ACE inhibitor quinaprilat with an intravenous infusion of sodium nitroprusside in 23 patients with chronic heart failure (NYHA Class III or IV). At the highest drug doses, sodium nitroprusside significantly increased stroke volume index (+6.63 ml/m(2), p=0.045), whereas quinaprilat induced only a minor increase (+1.79 ml/m(2), n.s.).

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