The gut microbiota elicits a profound metabolic reorientation in the mouse jejunal mucosa during conventionalisation.

Sahar El Aidy; Claire A Merrifield; Muriel Derrien; Peter van Baarlen; Guido Hooiveld; Florence Levenez; Joel Doré; Jan Dekker; Elaine Holmes; Sandrine P Claus; Dirk-Jan Reijngoud; Michiel Kleerebezem

doi:10.1136/gutjnl-2011-301955

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The gut microbiota elicits a profound metabolic reorientation in the mouse jejunal mucosa during conventionalisation.

Authors

El Aidy, Sahar
Merrifield, Claire A
Derrien, Muriel
van Baarlen, Peter
Hooiveld, Guido
Levenez, Florence
Doré, Joel
Dekker, Jan
Holmes, Elaine
Claus, Sandrine P
Reijngoud, Dirk-Jan
Kleerebezem, Michiel

Type

Published Article

Journal

Gut

Publisher

BMJ

Publication Date

Sep 01, 2013

Volume

62

Issue

9

Pages

1306–1314

Identifiers

DOI: 10.1136/gutjnl-2011-301955

PMID: 22722618

Source

Medline

Keywords

License

Unknown

Abstract

This study elucidates the dynamic jejunal response to the microbiota and supports a prominent role for the jejunum in metabolic control, including glucose and energy homoeostasis. The molecular signatures of this process may help to find risk markers in the declining insulin sensitivity seen in human type 2 diabetes mellitus, for instance.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 07/04/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/22722618

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