The gut microbiota elicits a profound metabolic reorientation in the mouse jejunal mucosa during conventionalisation.
- Authors
- Type
- Published Article
- Journal
- Gut
- Publisher
- BMJ
- Publication Date
- Sep 01, 2013
- Volume
- 62
- Issue
- 9
- Pages
- 1306–1314
- Identifiers
- DOI: 10.1136/gutjnl-2011-301955
- PMID: 22722618
- Source
- Medline
- Keywords
- License
- Unknown
Abstract
This study elucidates the dynamic jejunal response to the microbiota and supports a prominent role for the jejunum in metabolic control, including glucose and energy homoeostasis. The molecular signatures of this process may help to find risk markers in the declining insulin sensitivity seen in human type 2 diabetes mellitus, for instance.