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Growth rate of human tumour xenografts measured in nude mice by in vivo cast modelling.

Authors
  • Fiennes, A G
Type
Published Article
Journal
The British journal of surgery
Publication Date
Jan 01, 1988
Volume
75
Issue
1
Pages
23–24
Identifiers
PMID: 3337943
Source
Medline
License
Unknown

Abstract

Caliper measurement of xenograft tumour volume incurs shape-dependent errors of up to 230 per cent. A more sensitive and accurate method is described for repeated in vivo measurement of tumour volume by cast modelling. The technique can provide electronic data for further analysis and its accuracy and limitations can themselves be determined. Week-on-week changes in tumour volume may be detected with up to 99 per cent confidence.

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