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Growth properties of cardiac stem cells are a novel biomarker of patients' outcome after coronary bypass surgery.

Authors
  • D'Amario, Domenico
  • Leone, Antonio M
  • Iaconelli, Antonio
  • Luciani, Nicola
  • Gaudino, Mario
  • Kannappan, Ramaswamy
  • Manchi, Melissa
  • Severino, Anna
  • Shin, Sang Hun
  • Graziani, Francesca
  • Biasillo, Gina
  • Macchione, Andrea
  • Smaldone, Costantino
  • De Maria, Giovanni Luigi
  • Cellini, Carlo
  • Siracusano, Andrea
  • Ottaviani, Lara
  • Massetti, Massimo
  • Goichberg, Polina
  • Leri, Annarosa
  • And 2 more
Type
Published Article
Journal
Circulation
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Jan 14, 2014
Volume
129
Issue
2
Pages
157–172
Identifiers
DOI: 10.1161/CIRCULATIONAHA.113.006591
PMID: 24249720
Source
Medline
Keywords
License
Unknown

Abstract

The telomere-telomerase axis, population-doubling time, and insulin-like growth factor-1 receptor expression in CSCs, together with a high circulating level of insulin-like growth factor-1, represent a novel biomarker able to predict the evolution of ischemic cardiomyopathy following revascularization.

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