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Growth properties of cardiac stem cells are a novel biomarker of patients' outcome after coronary bypass surgery.

Authors
Type
Published Article
Journal
Circulation
0009-7322
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Volume
129
Issue
2
Pages
157–172
Identifiers
DOI: 10.1161/CIRCULATIONAHA.113.006591
PMID: 24249720
Source
Medline
Keywords
  • Coronary Artery Disease
  • Receptor, Igf Type 1
  • Stem Cells
  • Telomerase
  • Telomere
  • Ventricular Remodeling

Abstract

The telomere-telomerase axis, population-doubling time, and insulin-like growth factor-1 receptor expression in CSCs, together with a high circulating level of insulin-like growth factor-1, represent a novel biomarker able to predict the evolution of ischemic cardiomyopathy following revascularization.

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