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Growth differentiation factor 9 reverses activin A suppression of steroidogenic acute regulatory protein expression and progesterone production in human granulosa-lutein cells.

Authors
Type
Published Article
Journal
The Journal of Clinical Endocrinology & Metabolism
0021-972X
Publisher
The Endocrine Society
Publication Date
Volume
95
Issue
10
Identifiers
DOI: 10.1210/jc.2010-0477
PMID: 20660033
Source
Medline

Abstract

GDF9 attenuates the suppressive effects of activin A on StAR expression and progesterone production by increasing the expression of inhibin B, which acts as an activin A competitor.

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