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Graft survival in a rhesus renal transplant model after immunotoxin-mediated T-cell depletion is enhanced by mycophenolate and steroids.

Authors
  • Fechner, J H Jr
  • Dong, Y
  • Hong, X
  • Brunner, K G
  • Tsuchida, M
  • Neville, D
  • Scharff, J
  • Lee, F
  • Oberley, T D
  • Peters, D
  • Schultz, J M
  • Manthei, E R
  • Hamawy, M M
  • Knechtle, S J
Type
Published Article
Journal
Transplantation Journal
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Aug 27, 2001
Volume
72
Issue
4
Pages
581–587
Identifiers
PMID: 11544415
Source
Medline
License
Unknown

Abstract

A combination with MMF and steroids given for 4 days after renal allograft transplantation significantly increases GST in IT-treated monkeys. We hypothesize that MMF and steroids suppress the initial T-cell activation mediated by IT.

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