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Gold nanoparticles: interesting optical properties and recent applications in cancer diagnostics and therapy.

Authors
  • Huang, Xiaohua
  • Jain, Prashant K
  • El-Sayed, Ivan H
  • El-Sayed, Mostafa A
Type
Published Article
Journal
Nanomedicine
Publisher
Future Medicine
Publication Date
Oct 01, 2007
Volume
2
Issue
5
Pages
681–693
Identifiers
PMID: 17976030
Source
Medline
License
Unknown

Abstract

Recent years have seen tremendous progress in the design and study of nanomaterials geared towards biological and biomedical applications, most notable among these being the noble metal nanoparticles. In this review, we outline the surface-plasmon resonance-enhanced optical properties of colloidal gold nanoparticles directed towards recent biomedical applications with an emphasis on cancer diagnostics and therapeutics. Methods of molecular-specific diagnostics/detection of cancer, including strongly enhanced surface plasmon resonance light-scattering, surface-enhanced emission of gold nanorods and surface-enhanced Raman scattering, are described. We also discuss the plasmonic photothermal therapy of cancer achieved by using the strongly enhanced surface-plasmon resonance absorption of gold nanospheres and nanorods.

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