Glycation Reduces the Stability of ApoAI and Increases HDL Dysfunction in Diet-controlled Type 2 Diabetes.
Departement of Endocrinology and Metabolism, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195.
Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH 44272.
Department of Cellular & Molecular Medicine, Cleveland Clinic, Cleveland, OH 44195.
Department of Quantitative Health Sciences, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195.
Merck Research Laboratories, 2015 Galloping Hill Road, Kenilworth, NJ 07033.
Department of Hepatology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195.
- Published Article
The Journal of Clinical Endocrinology & Metabolism
The Endocrine Society
- Publication Date
Oct 25, 2017
The 2H2O method allows the detection of early in vivo impairments in HDL metabolism and function that are related to hyperglycemia-induced glycation of ApoAI in T2DM.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
This record was last updated on 06/09/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/29077935