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Glucose transporter 1 gene expression is related to thyroid neoplasms with an unfavorable prognosis: an immunohistochemical study.

Authors
  • Schönberger, Johann
  • Rüschoff, J
  • Grimm, Daniela
  • Marienhagen, Jörg
  • Rümmele, Petra
  • Meyringer, Rotraud
  • Kossmehl, Peter
  • Hofstaedter, Ferdinand
  • Eilles, Christoph
Type
Published Article
Journal
Thyroid : official journal of the American Thyroid Association
Publication Date
Sep 01, 2002
Volume
12
Issue
9
Pages
747–754
Identifiers
PMID: 12481939
Source
Medline
License
Unknown

Abstract

These data indicate that overexpression of GLUT1 on the cell membrane of thyroid neoplasms is closely related to tumors demonstrating a more aggressive biological behavior. Therefore, determination of GLUT1 expression in thyroid cancer tissue may be a prognostic marker, and FDG-PET may be a helpful technique in identifying patients at a higher risk.

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