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Global longitudinal strain is a more reproducible measure of left ventricular function than ejection fraction regardless of echocardiographic training

Authors
  • Karlsen, Sigve
  • Dahlslett, Thomas
  • Grenne, Bjørnar
  • Sjøli, Benthe
  • Smiseth, Otto
  • Edvardsen, Thor
  • Brunvand, Harald
Type
Published Article
Journal
Cardiovascular Ultrasound
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Sep 02, 2019
Volume
17
Issue
1
Identifiers
DOI: 10.1186/s12947-019-0168-9
Source
Springer Nature
Keywords
License
Green

Abstract

BackgroundLeft ventricular ejection fraction (LVEF) is an established method for evaluation of left ventricular (LV) systolic function. Global longitudinal strain (GLS) by speckle tracking echocardiography seems to be an important additive method for evaluation of LV function with improved reproducibility compared with LVEF. Our aim was to compare reproducibility of GLS and LVEF between an expert and trainee both as echocardiographic examiner and analyst.MethodsForty-seven patients with recent Acute Coronary Syndrome (ACS) underwent echocardiographic examination by both an expert echocardiographer and a trainee. Both echocardiographers, blinded for clinical data and each other’s findings, performed image analysis for evaluation of intra- and inter- observer variability. GLS was measured using speckle tracking echocardiography. LVEF was calculated by Simpson’s biplane method.ResultsThe trainee measured a GLS of − 19.4% (±3.5%) and expert − 18.7% (±3.2%) with an Intra class correlation coefficient (ICC) of 0.89 (0.74–0.95). LVEF by trainee was 50.3% (±8.2%) and by expert 53.6% (±8.6%), ICC coefficient was 0.63 (0.32–0.80). For GLS the systematic difference was 0.21% (− 4.58–2.64) vs. 4.08% (− 20.78–12.62) for LVEF.ConclusionGLS is a more reproducible method for evaluation of LV function than LVEF regardless of echocardiographic training.

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