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Global analysis of genes regulated by EvgA of the two-component regulatory system in Escherichia coli.

Authors
  • Nishino, Kunihiko
  • Inazumi, Yoshihiko
  • Yamaguchi, Akihito
Type
Published Article
Journal
Journal of bacteriology
Publication Date
Apr 01, 2003
Volume
185
Issue
8
Pages
2667–2672
Identifiers
PMID: 12670992
Source
Medline
License
Unknown

Abstract

The response regulator EvgA controls expression of multiple genes conferring antibiotic resistance in Escherichia coli (K. Nishino and A. Yamaguchi, J. Bacteriol. 184:2319-2323, 2002). To understand the whole picture of EvgA regulation, DNA macroarray analysis of the effect of EvgA overproduction was performed. EvgA activated genes related to acid resistance, osmotic adaptation, and drug resistance.

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