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Giant-cell tumor of bone with pathological evidence of blood vessel invasion.

Authors
  • Khalil, Shadi1
  • Yendala, Rachana1
  • D'Cunha, Nicholas1
  • Hardwicke, Fred1
  • Shanshal, Mohamed2
  • 1 Department of Hematology/Oncology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
  • 2 Department of Hematology/Oncology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. Electronic address: [email protected]
Type
Published Article
Journal
Hematology/Oncology and Stem Cell Therapy
Publisher
Elsevier
Publication Date
Sep 01, 2017
Volume
10
Issue
3
Pages
161–163
Identifiers
DOI: 10.1016/j.hemonc.2017.05.031
PMID: 28633039
Source
Medline
Keywords
License
Unknown

Abstract

Giant cell tumor of bone is a rare but aggressive benign tumor that arises at the end of long tubular bones. The tumor rarely metastasizes; however, we report a case in which a giant cell tumor of bone presented with progressive pulmonary metastases. There has been no clear pathologic evidence of the definitive cause or route of metastasis. In our case, the primary tumor site was located in the left femur with pathological evidence of blood vessel invasion. The histological and pathological features of this entity are discussed in this letter to the editor.

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