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Giant lymph node hyperplasia: a disease of primary follicle/mantle zone lymphocytes?

Authors
  • De Paoli, P
  • Carbone, A
  • Reitano, M
  • Volpe, R
  • Tirelli, U
  • Santini, G
Type
Published Article
Journal
Clinical immunology and immunopathology
Publication Date
Aug 01, 1986
Volume
40
Issue
2
Pages
371–374
Identifiers
PMID: 3487404
Source
Medline
License
Unknown

Abstract

Histological, immunohistochemical, and immunological features of a lymph node from a patient with Castleman's disease (CD), hyaline vascular type, were investigated. The results substantiate a peculiar immunological identity of this disease. CD lymph nodes consisted mainly of polyclonal primary follicle/mantle zone lymphocytes. Germinal center cells and plasma cells were absent, while T-lymphocyte subsets were not modified.

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