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Getting started: altering promoter choice as a mechanism for cell type differentiation.

Authors
  • Ray, Mukulika1
  • Larschan, Erica1
  • 1 Department of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, Rhode Island 02912, USA.
Type
Published Article
Journal
Genes & development
Publication Date
May 01, 2020
Volume
34
Issue
9-10
Pages
619–620
Identifiers
DOI: 10.1101/gad.338723.120
PMID: 32358039
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

In this issue of Genes & Development, Lu and colleagues (pp. 663-677) have discovered a key new mechanism of alternative promoter choice that is involved in differentiation of spermatocytes. Promoter choice has strong potential as mechanism for differentiation of many different cell types. © 2020 Ray and Larschan; Published by Cold Spring Harbor Laboratory Press.

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