Affordable Access

deepdyve-link
Publisher Website

The genus Daphne: A review of its traditional uses, phytochemistry and pharmacology.

Authors
  • Moshiashvili, Giorgi1
  • Tabatadze, Nino2
  • Mshvildadze, Vakhtang3
  • 1 I.Kutateladze Institute of Pharmacochemistry, Tbilisi State Medical Univercity, Tbilisi, Georgia. Electronic address: [email protected] , (Georgia)
  • 2 Faculty of Natural Sciences, Mathematics, Technology and Pharmacy, Sokhumi State University, Tbilisi, Georgia. , (Georgia)
  • 3 Department of Basic Sciences, University of Quebec, Chicoutimi, Canada. , (Canada)
Type
Published Article
Journal
Fitoterapia
Publication Date
Jun 01, 2020
Volume
143
Pages
104540–104540
Identifiers
DOI: 10.1016/j.fitote.2020.104540
PMID: 32165275
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

The genus Daphne belongs to the Thymeleaceae family and contains over 90 species that are distributed in Asia, Europe and parts of North Africa. The species of the genus Daphne are used in the traditional medicine of China, Tibet, Korea, and the Middle East for the treatment of various conditions. A broad range of studies has shown the significant biological potential of these species as sources of biologically and pharmacologically active compounds. Daphne species are a source of several classes of valuable phytochemicals such as coumarins, flavonoids, lignans, steroids and different classes of terpenes. The phytochemical diversity of this genus is demonstrated by over 350 secondary metabolites isolated from various species. The genus possesses a broad spectrum of biological activities including antibacterial, antifungal, antioxidant, analgesic, anti-inflammatory, cytotoxic, antiviral, abortive and haemostatic effects. A variety of bioactive secondary metabolites found in this genus may have potential use in pharmaceutical, cosmetic and food industries. Thus, species belonging to the genus Daphne can be considered an important source both for the treatment of various disorders, due to the presence of a plethora of bioactive constituents with potent bioactivities, and as possible leads in the discovery and synthesis of new medications. Copyright © 2020 Elsevier B.V. All rights reserved.

Report this publication

Statistics

Seen <100 times