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Gentamicin penetration and decay in the human aqueous.

Authors
Type
Published Article
Journal
The British journal of ophthalmology
Publication Date
Volume
63
Issue
11
Pages
794–796
Identifiers
PMID: 508697
Source
Medline
License
Unknown

Abstract

The penetration of gentamicin into human aqueous was measured after intensive drops or subconjunctival injection of the antibiotic. The drop regimen proved ineffective in producing a therapeutically effective level. After a single 40 mg subconjunctival injection an effective concentration was achieved in 2 hours and maintained for 24 hours. The significance of these findings is discussed with respect to therapeutic implications.

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