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Genomic information on Stenotrophomonas maltophilia ST264 isolated from a cystic fibrosis pediatric patient in Brazil.

Authors
  • Braga, Fabrina Seger1
  • D'Allincourt Carvalho Assef, Ana Paula2
  • Leão, Robson Souza1
  • Albano, Rodolpho Mattos3
  • Marques, Elizabeth Andrade4
  • 1 Departamento de Microbiologia, Imunologia e Parasitologia, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Avenida Boulevard 28 de Setembro, 87, fundos, 3° andar, Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil. , (Brazil)
  • 2 Laboratório de Pesquisa em Infecção Hospitalar (LAPIH), Instituto Oswaldo Cruz (FIOCRUZ), Avenida Brasil, 4.365, Pavilhão Rocha Lima - Sala 314, Manguinhos, Rio de Janeiro, RJ, 21040-360, Brazil. , (Brazil)
  • 3 Departamento de Bioquímica, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Avenida Boulevard 28 de Setembro, 87, 4°andar, Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil. , (Brazil)
  • 4 Departamento de Microbiologia, Imunologia e Parasitologia, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Avenida Boulevard 28 de Setembro, 87, fundos, 3° andar, Vila Isabel, Rio de Janeiro, RJ, 20551-030, Brazil. [email protected] , (Brazil)
Type
Published Article
Journal
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
Publication Date
Sep 01, 2020
Volume
51
Issue
3
Pages
1125–1127
Identifiers
DOI: 10.1007/s42770-019-00214-y
PMID: 31858443
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Stenotrophomonas maltophilia is one of the Gram-negative bacilli most frequently found in the airways of cystic fibrosis patients. This opportunistic pathogen is intrinsically multidrug-resistant, and therefore, its treatment presents a challenge. The genetic characterization of S. maltophilia is largely unknown, especially from those strains that colonize/infect the airways of cystic fibrosis patients. This work reports the draft genome sequences of three S. maltophilia isolates recovered from the sputum of a cystic fibrosis pediatric patient in Southeast Brazil. Several resistance- and virulence-related genes were detected. Furthermore, one intact phage and one incomplete prophage region were also identified in all strains. Multilocus sequence typing showed that all strains belonged to a new sequence type (ST264). Interestingly, all S. maltophilia strains were genetically identical, showing persistence for at least 16 months. To our knowledge, this is the first report of S. maltophilia draft genome sequences obtained from a cystic fibrosis pediatric patient in Brazil.

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