Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis
- Authors
- Type
- Published Article
- Journal
- Communications Biology
- Publisher
- Nature Publishing Group UK
- Publication Date
- May 17, 2021
- Volume
- 4
- Issue
- 1
- Identifiers
- DOI: 10.1038/s42003-021-02095-0
- Source
- Springer Nature
- License
- Green
Abstract
Ferrarini & Lal et al. developed a novel bioinformatic pipeline to explore how SARS-CoV-2 interacts with human respiratory cells using public available host gene expression and viral genome sequence data. Several human genes and proteins were predicted to play a role in the viral life cycle and the host response to SARS-CoV-2 infection.