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Genomes in turmoil: quantification of genome dynamics in prokaryote supergenomes.

Authors
  • Puigbò, Pere
  • Lobkovsky, Alexander E
  • Kristensen, David M
  • Wolf, Yuri I
  • Koonin, Eugene V
Type
Published Article
Journal
BMC Biology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Aug 21, 2014
Volume
12
Pages
66–66
Identifiers
DOI: 10.1186/s12915-014-0066-4
PMID: 25141959
Source
Medline
License
Unknown

Abstract

Reconstruction of evolution for groups of closely related bacteria and archaea reveals an extremely rapid and highly variable flux of genes in evolving microbial genomes, demonstrates that extensive gene loss and horizontal gene transfer leading to innovation are the two dominant evolutionary processes, and yields robust estimates of the supergenome size.

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